Number of amino acids: 362
Molecular weight: 39333.3
Theoretical pI: 4.76
Amino acid composition:
Ala (A) 34 9.4%
Arg (R) 12 3.3%
Asn (N) 32 8.8%
Asp (D) 27 7.5%
Cys (C) 0 0.0%
Gln (Q) 13 3.6%
Glu (E) 14 3.9%
Gly (G) 49 13.5%
His (H) 1 0.3%
Ile (I) 14 3.9%
Leu (L) 23 6.4%
Lys (K) 19 5.2%
Met (M) 5 1.4%
Phe (F) 19 5.2%
Pro (P) 5 1.4%
Ser (S) 16 4.4%
Thr (T) 22 6.1%
Trp (W) 2 0.6%
Tyr (Y) 29 8.0%
Val (V) 26 7.2%
Asx (B) 0 0.0%
Glx (Z) 0 0.0%
Xaa (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 41
Total number of positively charged residues (Arg + Lys): 31
Atomic composition:
Carbon C 1755
Hydrogen H 2634
Nitrogen N 466
Oxygen O 557
Sulfur S 5
Formula: C1755H2634N466O557S5Total number of atoms: 5417
Extinction coefficients:
Extinction coefficients are in units of M-1 cm-1, at 280 nm.
Ext. coefficient 54210
Abs 0.1% (=1 g/l) 1.378, assuming ALL Cys residues appear as half cystines
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 13.81
This classifies the protein as stable.
Aliphatic index: 70.08
Grand average of hydropathicity (GRAVY): -0.398
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Please note the modified algorithm for extinction coefficient.